SCN2B antibody (Internal Region)

Catalog No. ABIN6258329

Product Details anti-SCN2B Antibody

Target: SCN2B (Sodium Channel, Voltage-Gated, Type II, beta (SCN2B))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: SCN2B Antibody detects endogenous levels of total SCN2B.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SCN2B, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SCN2B

Target: SCN2B (Sodium Channel, Voltage-Gated, Type II, beta (SCN2B))

Alternative Name: SCN2B (SCN2B Products)

Synonyms: SCNB2 antibody, 2810451E09Rik antibody, AI840361 antibody, Gm183 antibody, SCN2B antibody, sodium voltage-gated channel beta subunit 2 antibody, sodium channel, voltage-gated, type II, beta antibody, sodium voltage-gated channel beta subunit 2 L homeolog antibody, SCN2B antibody, Scn2b antibody, scn2b.L antibody, scn2b antibody

Background:

Description: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).

Gene: SCN2B

Molecular Weight: 24 kDa

Gene ID: 6327

UniProt: O60939