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CHRNA10 antibody (C-Term)

CHRNA10 Reactivity: Human, Mouse, Rat ELISA, ICC, IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258708
$390.77
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  • Target See all CHRNA10 Antibodies
    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
    Binding Specificity
    • 9
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 36
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRNA10 antibody is un-conjugated
    Application
    • 29
    • 21
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
    Specificity
    CHRNA10 Antibody detects endogenous levels of total CHRNA10.
    Predicted Reactivity
    Pig,Bovine,Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CHRNA10, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
    Alternative Name
    CHRNA10 (CHRNA10 Products)
    Synonyms
    si:dkey-24p1.3 antibody, ALPHA 10 nAChR antibody, cholinergic receptor, nicotinic, alpha polypeptide 10 antibody, cholinergic receptor nicotinic alpha 10 subunit antibody, cholinergic receptor, nicotinic, alpha 10a antibody, neuronal acetylcholine receptor subunit alpha-10 antibody, cholinergic receptor, nicotinic, alpha 10 (neuronal) antibody, Chrna10 antibody, CHRNA10 antibody, chrna10a antibody, LOC100344381 antibody
    Background

    Description: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

    Gene: CHRNA10

    Molecular Weight
    50 kDa
    Gene ID
    57053
    UniProt
    Q9GZZ6
    Pathways
    Sensory Perception of Sound, Synaptic Membrane
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