CHRNA10 antibody

Catalog No. ABIN7242320

The Rabbit Polyclonal anti-CHRNA10 antibody (ABIN7242320) specifically detects CHRNA10 in ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for CHRNA10 antibody (ABIN7242320)

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA10 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CHRNA10 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human CHRNA10

Isotype: IgG

Application Details

Application Notes: IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRNA10

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Alternative Name: CHRNA10

Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

NCBI Accession: NP_065135

UniProt: Q9GZZ6

Pathways: Sensory Perception of Sound, Synaptic Membrane