GBP2 antibody (Internal Region)

Catalog No. ABIN6258917

Product Details anti-GBP2 Antibody

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: GBP2 Antibody detects endogenous levels of total GBP2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GBP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for GBP2

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Alternative Name: GBP2 (GBP2 Products)

Synonyms: guanylate binding protein 2 antibody, guanylate binding protein 2, interferon-inducible antibody, GTP binding protein 2 L homeolog antibody, GBP2 antibody, Gbp2 antibody, gtpbp2.L antibody

Background:

Description: Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (PubMed:8706832). Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).

Gene: GBP2

Molecular Weight: 67 kDa

Gene ID: 2634

UniProt: P32456

Pathways: Cellular Response to Molecule of Bacterial Origin