KCNE2 antibody (Internal Region)
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- Target See all KCNE2 Antibodies
- KCNE2 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 2 (KCNE2))
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Binding Specificity
- Internal Region
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KCNE2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- KCNE2 Antibody detects endogenous levels of total KCNE2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human KCNE2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product KCNE2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- KCNE2 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 2 (KCNE2))
- Alternative Name
- KCNE2 (KCNE2 Products)
- Synonyms
- ATFB4 antibody, LQT5 antibody, LQT6 antibody, MIRP1 antibody, Mirp1 antibody, MiRP1 antibody, 2200002I16Rik antibody, AW048273 antibody, potassium voltage-gated channel subfamily E regulatory subunit 2 antibody, potassium voltage-gated channel, Isk-related subfamily, gene 2 antibody, KCNE2 antibody, Kcne2 antibody
- Background
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Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with HCN1 and HCN2 and increase potassium current. Interacts with KCNQ1, forms a heterooligomer complex leading to currents with an apparently instantaneous activation, a rapid deactivation process and a linear current-voltage relationship and decreases the amplitude of the outward current (PubMed:11101505).
Gene: KCNE2
- Molecular Weight
- ?14 kDa
- Gene ID
- 9992
- UniProt
- Q9Y6J6
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