ITGB6 antibody (Internal Region)

Catalog No. ABIN6259456

Product Details anti-ITGB6 Antibody

Target: ITGB6 (Integrin beta-6 (ITGB6))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: ITGB6 Antibody detects endogenous levels of total ITGB6.

Predicted Reactivity: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ITGB6, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ITGB6

Target: ITGB6 (Integrin beta-6 (ITGB6))

Alternative Name: ITGB6 (ITGB6 Products)

Synonyms: 2210409C20Rik antibody, 4831415H04Rik antibody, ITB6 antibody, integrin subunit beta 6 antibody, integrin beta 6 antibody, ITGB6 antibody, Itgb6 antibody

Background:

Description: Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881).

Gene: ITGB6

Molecular Weight: 86 kDa

Gene ID: 3694

UniProt: P18564