ANG antibody (Internal Region)
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- Target See all ANG Antibodies
- ANG (Angiogenin (ANG))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ANG antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- Angiogenin Antibody detects endogenous levels of total Angiogenin.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Angiogenin, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ANG Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ANG (Angiogenin (ANG))
- Alternative Name
- ANG (ANG Products)
- Synonyms
- ALS9 antibody, HEL168 antibody, RNASE4 antibody, RNASE5 antibody, ANG antibody, AI385586 antibody, Ang1 antibody, Rnase5 antibody, Rnase5a antibody, ANG1 antibody, angiogenin antibody, angiogenin, ribonuclease, RNase A family, 5 antibody, ribonuclease A family member k6 antibody, ANG antibody, Ang antibody, RNASE6 antibody
- Background
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Description: Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
Gene: ANG
- Molecular Weight
- 17kDa
- Gene ID
- 283
- UniProt
- P03950
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