EMSY antibody (Internal Region)

Catalog No. ABIN6260355

Product Details anti-EMSY Antibody

Target: EMSY (C11orf30) (Chromosome 11 Open Reading Frame 30 (C11orf30))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMSY antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: C11orf30 Antibody detects endogenous levels of total C11orf30.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human C11orf30, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for EMSY

Target: EMSY (C11orf30) (Chromosome 11 Open Reading Frame 30 (C11orf30))

Alternative Name: EMSY (C11orf30 Products)

Synonyms: 2210018M11RIK antibody, EMSY antibody, 2310016L09Rik antibody, AU019521 antibody, AU019557 antibody, Emsy antibody, emsy antibody, fj36b04 antibody, wu:fj36b04 antibody, EMSY, BRCA2 interacting transcriptional repressor antibody, EMSY, BRCA2-interacting transcriptional repressor antibody, EMSY BRCA2-interacting transcriptional repressor antibody, EMSY antibody, Emsy antibody, emsy antibody

Background:

Description: Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.

Gene: EMSY

Molecular Weight: 150 kDa

Gene ID: 56946

UniProt: Q7Z589