ZFC3H1 antibody (Internal Region)

Catalog No. ABIN6260527

Product Details anti-ZFC3H1 Antibody

Target: ZFC3H1 (Zinc Finger, C3H1-Type Containing (ZFC3H1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFC3H1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: CCDC131 Antibody detects endogenous levels of total CCDC131.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCDC131, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ZFC3H1

Target: ZFC3H1 (Zinc Finger, C3H1-Type Containing (ZFC3H1))

Alternative Name: ZFC3H1 (ZFC3H1 Products)

Synonyms: CCDC131 antibody, PSRC2 antibody, Psrc2 antibody, RGD1306287 antibody, zinc finger C3H1-type containing antibody, zinc finger, C3H1-type containing antibody, ZFC3H1 antibody, Zfc3h1 antibody

Background:

Description: Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters.

Gene: ZFC3H1

Molecular Weight: 226 kDa

Gene ID: 196441

UniProt: O60293