CCDC8 antibody (N-Term)

Catalog No. ABIN6260529

Product Details anti-CCDC8 Antibody

Target: CCDC8 (Coiled-Coil Domain Containing 8 (CCDC8))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: CCDC8 Antibody detects endogenous levels of total CCDC8.

Predicted Reactivity: Pig,Bovine,Horse,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCDC8, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CCDC8

Target: CCDC8 (Coiled-Coil Domain Containing 8 (CCDC8))

Alternative Name: CCDC8 (CCDC8 Products)

Synonyms: 3M3 antibody, PPP1R20 antibody, p90 antibody, ENSMUSG00000041117 antibody, coiled-coil domain containing 8 antibody, CCDC8 antibody, Ccdc8 antibody

Background:

Description: Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of CUL7 to the centrosome (PubMed:24793695).

Gene: CCDC8

Molecular Weight: 59 kDa

Gene ID: 83987

UniProt: Q9H0W5