CYP4F2 antibody (N-Term)
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- Target See all CYP4F2 Antibodies
- CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP4F2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Specificity
- CYP4F2 Antibody detects endogenous levels of total CYP4F2.
- Predicted Reactivity
- Pig,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CYP4F2, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product CYP4F2 Primary Antibody
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- Application Notes
- WB 1:1000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))
- Alternative Name
- CYP4F2 (CYP4F2 Products)
- Synonyms
- CPF2 antibody, MGC126966 antibody, cytochrome P450 family 4 subfamily F member 2 antibody, cytochrome P450, family 4, subfamily F, polypeptide 2 antibody, cytochrome P450 family 4 subfamily F member 2 L homeolog antibody, CYP4F2 antibody, cyp4f2.L antibody
- Background
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Description: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B4 omega-hydroxylase by mediating conversion of leukotriene-B4 (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B4 (20-OH LTB4) (PubMed:8026587, PubMed:9799565).
Gene: CYP4F2
- Molecular Weight
- 60kDa
- Gene ID
- 8529
- UniProt
- P78329
- Pathways
- Monocarboxylic Acid Catabolic Process
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