EPB41 antibody (Internal Region)

Catalog No. ABIN6261547

Product Details anti-EPB41 Antibody

Target: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPB41 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: EPB41 Antibody detects endogenous levels of total EPB41.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EPB41, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for EPB41

Target: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Alternative Name: EPB41 (EPB41 Products)

Synonyms: P4.1R antibody, epb41 antibody, wu:fb70c02 antibody, EPB41 antibody, el1 antibody, 4.1r antibody, 4.1R antibody, EL1 antibody, HE antibody, AI415518 antibody, D4Ertd442e antibody, Elp-1 antibody, Elp1 antibody, Epb41 antibody, mKIAA4056 antibody, erythrocyte membrane protein band 4.1b antibody, erythrocyte membrane protein band 4.1 antibody, erythrocyte membrane protein band 4.1 L homeolog antibody, epb41b antibody, EPB41 antibody, epb41 antibody, epb41.L antibody, Epb41 antibody

Background:

Description: Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127).

Gene: EPB41

Molecular Weight: 97kDa

Gene ID: 2035

UniProt: P11171