GLUD1 antibody (Internal Region)

Catalog No. ABIN6261983

Product Details anti-GLUD1 Antibody

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLUD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: GLUD1 Antibody detects endogenous levels of total GLUD1.

Predicted Reactivity: Bovine,Sheep,Rabbit,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GLUD1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GLUD1

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Alternative Name: GLUD1 (GLUD1 Products)

Synonyms: GDH antibody, gdh1 antibody, GDH 1 antibody, glud1 antibody, GLUD1 antibody, cb719 antibody, wu:fb16e02 antibody, wu:fb58f12 antibody, wu:fe37f03 antibody, wu:fj43f02 antibody, zgc:192851 antibody, zgc:55630 antibody, GDH1 antibody, GLUD antibody, AI118167 antibody, Gdh-X antibody, Glud antibody, Gludl antibody, Ac2-281 antibody, Gdh1 antibody, Gludeha antibody, MRG-2 antibody, GLUTAMATE DECARBOXYLASE 1 antibody, GLUTAMATE DEHYDROGENASE 1 antibody, MRG7.13 antibody, MRG7_13 antibody, glutamate dehydrogenase 1 antibody, C2H1orf130 antibody, legdh1 antibody, cb622 antibody, wu:fc33g09 antibody, wu:fc66a10 antibody, zgc:77186 antibody, glutamate dehydrogenase 1 antibody, glutamate dehydrogenase 1 S homeolog antibody, glutamate dehydrogenase 1, mitochondrial antibody, glutamate dehydrogenase 1b antibody, glutamate dehydrogenase antibody, non-compact myelin associated protein antibody, glutamate dehydrogenase 1a antibody, GLUD1 antibody, GDH1 antibody, glud1 antibody, glud1.S antibody, LOC693461 antibody, glud1b antibody, Glud1 antibody, HACJB3_RS00320 antibody, LOC100587725 antibody, NCMAP antibody, gdh1 antibody, glud1a antibody

Background:

Description: Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).

Gene: GLUD1

Molecular Weight: 45-55 kDa

Gene ID: 2746

UniProt: P00367

Pathways: Positive Regulation of Peptide Hormone Secretion, Warburg Effect