GRB7 antibody (Internal Region)
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- Target See all GRB7 Antibodies
- GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GRB7 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- GRB7 Antibody detects endogenous levels of total GRB7.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GRB7, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GRB7 Primary Antibody
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anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 298-489) antibody
GRB7 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 1-532) antibodyGRB7 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 1-532) antibodyGRB7 Reactivity: Human WB, FACS Host: Mouse Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 66-327) antibodyGRB7 Reactivity: Human WB, ELISA, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 37-136) antibodyGRB7 Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 3C12 unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 233-532) antibodyGRB7 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) antibodyGRB7 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 124-141), (Middle Region) antibodyGRB7 Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 289-318) antibodyGRB7 Reactivity: Human WB Host: Rabbit Polyclonal RB22989 unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (N-Term) antibodyVerified GRB7 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
- Alternative Name
- GRB7 (GRB7 Products)
- Synonyms
- GRB7 antibody, mKIAA4028 antibody, growth factor receptor bound protein 7 antibody, GRB7 antibody, Grb7 antibody
- Background
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Description: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).
Gene: GRB7
- Molecular Weight
- 60 kDa
- Gene ID
- 2886
- UniProt
- Q14451
- Pathways
- EGFR Signaling Pathway, Ribonucleoprotein Complex Subunit Organization
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