GUCA2B antibody (Internal Region)

Catalog No. ABIN6262130

Product Details anti-GUCA2B Antibody

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCA2B antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: GUCA2B Antibody detects endogenous levels of total GUCA2B.

Predicted Reactivity: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GUCA2B, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GUCA2B

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Alternative Name: GUCA2B (GUCA2B Products)

Synonyms: GUCA2B antibody, AV066530 antibody, Gcap2 antibody, Ugn antibody, GCAP-II antibody, UGN antibody, guanylate cyclase activator 2B antibody, guanylate cyclase activator 2b (retina) antibody, GUCA2B antibody, Guca2b antibody

Background:

Description: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.

Gene: GUCA2B

Molecular Weight: 12 kDa

Gene ID: 2981

UniProt: Q16661