ICT1 antibody

Catalog No. ABIN6262440

Product Details anti-ICT1 Antibody

Target: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: ICT1 antibody detects endogenous levels of ICT1.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ICT1.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for ICT1

Target: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Alternative Name: ICT1 (ICT1 Products)

Synonyms: ICT1 antibody, DS-1 antibody, DS1 antibody, 1110001A02Rik antibody, 1110002E03Rik antibody, mitochondrial ribosomal protein L58 antibody, imitochondrial ribosomal protein L58 S homeolog antibody, Immature colon carcinoma transcript 1 antibody, MRPL58 antibody, mrpl58.S antibody, PVX_091510 antibody, mrpl58 antibody, Mrpl58 antibody, ict1 antibody

Background:

Description: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Gene: MRPL58

Molecular Weight: 21-24 kDa

Gene ID: 3396

UniProt: Q14197