IFITM2 antibody

Catalog No. ABIN6262458

Product Details anti-IFITM2 Antibody

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: IFM2 Antibody detects endogenous levels of total IFM2

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IFM2

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for IFITM2

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Alternative Name: IFM2 (IFITM2 Products)

Synonyms: 1-8D antibody, DSPA2c antibody, Ifitm3l antibody, fragilis3 antibody, mil-3 antibody, Ifitml antibody, interferon induced transmembrane protein 2 antibody, IFITM2 antibody, Ifitm2 antibody

Background:

Description: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Gene: IFITM2

Molecular Weight: 14 kDa

Gene ID: 10581

UniProt: Q01629, P13164, Q01628