IGHMBP2 antibody (Internal Region)

Catalog No. ABIN6262501

Product Details anti-IGHMBP2 Antibody

Target: IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGHMBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: IGHMBP2 Antibody detects endogenous levels of total IGHMBP2.

Predicted Reactivity: Pig,Zebrafish,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IGHMBP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for IGHMBP2

Target: IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))

Alternative Name: IGHMBP2 (IGHMBP2 Products)

Synonyms: NV12364 antibody, CATF1 antibody, HCSA antibody, HMN6 antibody, SMARD1 antibody, SMUBP2 antibody, ZFAND7 antibody, AEP antibody, Catf1 antibody, RIPE3b1 antibody, Smbp-2 antibody, Smbp2 antibody, Smubp2 antibody, nmd antibody, sma antibody, RIP-1 antibody, RIP1 antibody, immunoglobulin mu binding protein 2 antibody, IGHMBP2 antibody, Ighmbp2 antibody, ighmbp2 antibody

Background:

Description: 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation (By similarity). DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.

Gene: IGHMBP2

Molecular Weight: 109kDa

Gene ID: 3508

UniProt: P38935