IL1RL2 antibody (Internal Region)

Catalog No. ABIN6262575

Product Details anti-IL1RL2 Antibody

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: ILRL2 Antibody detects endogenous levels of total ILRL2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ILRL2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for IL1RL2

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Alternative Name: IL1RL2 (IL1RL2 Products)

Synonyms: IL-1Rrp2 antibody, IL-36R antibody, IL1R-rp2 antibody, IL1RRP2 antibody, AI481289 antibody, AW551444 antibody, interleukin 1 receptor like 2 antibody, interleukin 1 receptor-like 2 antibody, IL1RL2 antibody, Il1rl2 antibody

Background:

Description: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response, it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

Gene: IL1RL2

Molecular Weight: 65 kDa

Gene ID: 8808

UniProt: Q9HB29