MAN1B1 antibody (Internal Region)
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- Target See all MAN1B1 Antibodies
- MAN1B1 (Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))
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Binding Specificity
- Internal Region
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAN1B1 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- MAN1B1 Antibody detects endogenous levels of total MAN1B1.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MAN1B1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MAN1B1 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MAN1B1 (Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))
- Alternative Name
- MAN1B1 (MAN1B1 Products)
- Synonyms
- erman1 antibody, mana-er antibody, MAN1B1 antibody, ERMAN1 antibody, MANA-ER antibody, MRT15 antibody, E430019H13Rik antibody, ERMan1 antibody, Gm108 antibody, RGD1563595 antibody, mannosidase alpha class 1B member 1 antibody, mannosidase, alpha, class 1B, member 1 L homeolog antibody, endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase antibody, mannosidase, alpha, class 1B, member 1 antibody, MAN1B1 antibody, man1b1.L antibody, LOC480667 antibody, man1b1 antibody, Man1b1 antibody
- Background
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Description: Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2.
Gene: MAN1B1
- Molecular Weight
- 80kDa
- Gene ID
- 11253
- UniProt
- Q9UKM7
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