MKS1 antibody

Catalog No. ABIN6263271

Product Details anti-MKS1 Antibody

Target: MKS1 (Meckel Syndrome, Type 1 (MKS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: MKS1 antibody detects endogenous levels of MKS1.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MKS1.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for MKS1

Target: MKS1 (Meckel Syndrome, Type 1 (MKS1))

Alternative Name: MKS1 (MKS1 Products)

Synonyms: BBS13 antibody, MES antibody, MKS antibody, POC12 antibody, AK190930 antibody, B8d3 antibody, Meckel syndrome, type 1 antibody, MKS1 antibody, Mks1 antibody

Background:

Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.

Gene: MKS1

Molecular Weight: 65-70 kDa

Gene ID: 54903

UniProt: Q9NXB0