KIF20B antibody (N-Term)
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- Target See all KIF20B Antibodies
- KIF20B (Kinesin Family Member 20B (KIF20B))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KIF20B antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- MPP1 Antibody detects endogenous levels of total MPP1.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MPP1, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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- Application Notes
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- KIF20B (Kinesin Family Member 20B (KIF20B))
- Alternative Name
- KIF20B (KIF20B Products)
- Synonyms
- ct90 antibody, mpp1 antibody, krmp1 antibody, mpp-1 antibody, MGC83846 antibody, mphosph1 antibody, KIF20B antibody, MPHOSPH1 antibody, CT90 antibody, KRMP1 antibody, MPP-1 antibody, MPP1 antibody, B130024C23 antibody, C330014J10Rik antibody, Mphosph1 antibody, kinesin family member 20B S homeolog antibody, kinesin family member 20B antibody, kif20b.S antibody, KIF20B antibody, kif20b antibody, Kif20b antibody
- Background
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Description: Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).
Gene: KIF20B
- Molecular Weight
- 210kDa
- Gene ID
- 9585
- UniProt
- Q96Q89
- Pathways
- M Phase
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