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KIF20B antibody (N-Term)

KIF20B Reactivity: Human, Mouse ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6263339
  • Target See all KIF20B Antibodies
    KIF20B (Kinesin Family Member 20B (KIF20B))
    Binding Specificity
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 12
    • 1
    • 1
    Human, Mouse
    Host
    • 11
    • 1
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    This KIF20B antibody is un-conjugated
    Application
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    MPP1 Antibody detects endogenous levels of total MPP1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MPP1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    KIF20B (Kinesin Family Member 20B (KIF20B))
    Alternative Name
    KIF20B (KIF20B Products)
    Synonyms
    ct90 antibody, mpp1 antibody, krmp1 antibody, mpp-1 antibody, MGC83846 antibody, mphosph1 antibody, KIF20B antibody, MPHOSPH1 antibody, CT90 antibody, KRMP1 antibody, MPP-1 antibody, MPP1 antibody, B130024C23 antibody, C330014J10Rik antibody, Mphosph1 antibody, kinesin family member 20B S homeolog antibody, kinesin family member 20B antibody, kif20b.S antibody, KIF20B antibody, kif20b antibody, Kif20b antibody
    Background

    Description: Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).

    Gene: KIF20B

    Molecular Weight
    210kDa
    Gene ID
    9585
    UniProt
    Q96Q89
    Pathways
    M Phase
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