MARCKSL1 antibody (Internal Region)

Catalog No. ABIN6263357

Product Details anti-MARCKSL1 Antibody

Target: MARCKSL1 (MARCKS-Like 1 (MARCKSL1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCKSL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: MRP Antibody detects endogenous levels of total MRP.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MRP, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MARCKSL1

Target: MARCKSL1 (MARCKS-Like 1 (MARCKSL1))

Alternative Name: MARCKSL1 (MARCKSL1 Products)

Synonyms: F52 antibody, MACMARCKS antibody, MLP antibody, MLP1 antibody, MRP antibody, AL022768 antibody, AW215397 antibody, AW536807 antibody, D4Bc1 antibody, MacMARCKS antibody, Macs2 antibody, Macs3 antibody, Mlp antibody, Mrp antibody, cb575 antibody, marcks1 antibody, marcksl1 antibody, sb:cb575 antibody, wu:fa66h03 antibody, wu:fj18a04 antibody, zgc:65840 antibody, MARCKSL1 antibody, f52 antibody, mlp antibody, mrp antibody, mlp1 antibody, macmarcks antibody, XMLP antibody, MARCKS like 1 antibody, MARCKS-like 1 antibody, MARCKS-like 1a antibody, MARCKS-like 1 L homeolog antibody, MARCKS-related protein antibody, MARCKS-like 1 S homeolog antibody, MARCKSL1 antibody, Marcksl1 antibody, marcksl1a antibody, marcksl1 antibody, marcksl1.L antibody, mrp antibody, marcksl1.S antibody

Background:

Description: Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity).

Gene: MARCKSL1

Molecular Weight: 20 kDa

Gene ID: 65108

UniProt: P49006