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MTR4 antibody (Internal Region)

SKIV2L2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6263426
  • Target See all MTR4 (SKIV2L2) Antibodies
    MTR4 (SKIV2L2) (Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2))
    Binding Specificity
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 26
    • 14
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 26
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTR4 antibody is un-conjugated
    Application
    • 15
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity
    MTR4 Antibody detects endogenous levels of total MTR4.
    Predicted Reactivity
    Pig,Bovine,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MTR4, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SKIV2L2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    MTR4 (SKIV2L2) (Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2))
    Alternative Name
    SKIV2L2 (SKIV2L2 Products)
    Synonyms
    RGD1305984 antibody, zgc:63838 antibody, wu:fd11a05 antibody, SKIV2L2 antibody, skiv2l2 antibody, Dob1 antibody, KIAA0052 antibody, Mtr4 antibody, fSAP118 antibody, 2610528A15Rik antibody, mKIAA0052 antibody, Ski2 like RNA helicase 2 antibody, superkiller viralicidic activity 2-like 2 antibody, superkiller viralicidic activity 2-like 2 (S. cerevisiae) antibody, Skiv2l2 antibody, skiv2l2 antibody, SKIV2L2 antibody, LOC100380870 antibody
    Background

    Description: Component of exosome targeting complexes. Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters (PubMed:27871484). May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA.

    Gene: SKIV2L2

    Molecular Weight
    118kDa
    Gene ID
    23517
    UniProt
    P42285
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