NEK8 antibody (Internal Region)

Catalog No. ABIN6263594

Product Details anti-NEK8 Antibody

Target: NEK8 (NIMA-Related Kinase 8 (NEK8))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEK8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: NEK8 Antibody detects endogenous levels of total NEK8.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NEK8, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NEK8

Target: NEK8 (NIMA-Related Kinase 8 (NEK8))

Alternative Name: NEK8 (NEK8 Products)

Synonyms: JCK antibody, NEK12A antibody, NPHP9 antibody, jck antibody, nphp9 antibody, nek12a antibody, MGC80499 antibody, 4632401F23Rik antibody, b2b1449Clo antibody, NIMA related kinase 8 antibody, NIMA-related kinase 8 antibody, NIMA-related kinase 8 S homeolog antibody, NIMA (never in mitosis gene a)-related expressed kinase 8 antibody, NEK8 antibody, nek8 antibody, nek8.S antibody, Nek8 antibody

Background:

Description: Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia (By similarity). Plays a role in organogenesis and is involved in the regulation of the Hippo signaling pathway.

Gene: NEK8

Molecular Weight: 75kDa

Gene ID: 284086

UniProt: Q86SG6