Neuregulin 4 antibody (C-Term)

Catalog No. ABIN6263735

This Rabbit Polyclonal antibody specifically detects Neuregulin 4 in IHC, WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Neuregulin 4 antibody (C-Term) (ABIN6263735)

Target: Neuregulin 4 (NRG4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-Neuregulin 4 Antibody

Binding Specificity: C-Term

Specificity: NRG4 Antibody detects endogenous levels of total NRG4.

Predicted Reactivity: Pig,Horse,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NRG4, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:100, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Neuregulin 4

Target: Neuregulin 4 (NRG4)

Alternative Name: NRG4

Background:

Description: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).

Gene: NRG4

Molecular Weight: 12kDa

Gene ID: 145957

UniProt: Q8WWG1

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway