MAPK4 antibody (Internal Region)

Catalog No. ABIN6263988

Product Details anti-MAPK4 Antibody

Target: MAPK4 (Mitogen-Activated Protein Kinase 4 (MAPK4))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: P63 MAPK Antibody detects endogenous levels of total p63 MAPK.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human p63 MAPK, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MAPK4

Target: MAPK4 (Mitogen-Activated Protein Kinase 4 (MAPK4))

Alternative Name: MAPK4 (MAPK4 Products)

Synonyms: ERK-4 antibody, ERK3 antibody, Erk4 antibody, MAPK 4 antibody, PRKM4 antibody, p63MAPK antibody, A330097D03Rik antibody, Erk3 antibody, Prkm4 antibody, p63Mapk antibody, erk4 antibody, wu:fi27d11 antibody, zgc:55498 antibody, ATMPK4 antibody, F2N1.1 antibody, F2N1_1 antibody, MAP kinase 4 antibody, mitogen-activated protein kinase 4 antibody, MAP kinase 4 antibody, MAPK4 antibody, Mapk4 antibody, mapk4 antibody, MPK4 antibody

Background:

Description: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).

Gene: MAPK4

Molecular Weight: 66 kDa

Gene ID: 5596

UniProt: P31152

Pathways: MAPK Signaling