PIGW antibody (Internal Region)

Catalog No. ABIN6264208

Product Details anti-PIGW Antibody

Target: PIGW (Phosphatidylinositol Glycan W (PIGW))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGW antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: PIGW Antibody detects endogenous levels of total PIGW.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PIGW, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PIGW

Target: PIGW (Phosphatidylinositol Glycan W (PIGW))

Alternative Name: PIGW (PIGW Products)

Synonyms: Gwt1 antibody, PIG-W antibody, 2610044A17Rik antibody, phosphatidylinositol glycan anchor biosynthesis class W antibody, phosphatidylinositol glycan anchor biosynthesis, class W antibody, PIGW antibody, Pigw antibody

Background:

Description: Required for the transport of GPI-anchored proteins to the plasma membrane (PubMed:24367057). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity).

Gene: PIGW

Molecular Weight: 57 kDa

Gene ID: 284098

UniProt: Q7Z7B1

Pathways: Inositol Metabolic Process