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RNF6 antibody (Internal Region)

RNF6 Reactivity: Human WB, ELISA, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264791
  • Target See all RNF6 Antibodies
    RNF6 (RING Finger Protein 6 (RNF6))
    Binding Specificity
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 50
    • 19
    • 19
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 46
    • 6
    Rabbit
    Clonality
    • 49
    • 3
    Polyclonal
    Conjugate
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF6 antibody is un-conjugated
    Application
    • 46
    • 22
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Specificity
    RNF6 Antibody detects endogenous levels of total RNF6.
    Predicted Reactivity
    Horse
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RNF6, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RNF6 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    RNF6 (RING Finger Protein 6 (RNF6))
    Alternative Name
    RNF6 (RNF6 Products)
    Synonyms
    1200013I08Rik antibody, 5730419H05Rik antibody, AA537053 antibody, ring finger protein 6 antibody, ring finger protein (C3H2C3 type) 6 antibody, RNF6 antibody, Rnf6 antibody
    Background

    Description: E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.

    Gene: RNF6

    Molecular Weight
    78kDa
    Gene ID
    6049
    UniProt
    Q9Y252
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size
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