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SENP2 antibody

SENP2 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264984
  • Target See all SENP2 Antibodies
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Reactivity
    • 38
    • 31
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 47
    • 7
    Rabbit
    Clonality
    • 47
    • 7
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SENP2 antibody is un-conjugated
    Application
    • 44
    • 18
    • 17
    • 13
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    SENP2 Antibody detects endogenous levels of total SENP2
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SENP2
    Isotype
    IgG
    Top Product
    Discover our top product SENP2 Primary Antibody
  • Application Notes
    WB 1:1000-3000 IF/ICC 1:200-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Alternative Name
    SENP2 (SENP2 Products)
    Synonyms
    2310007L05Rik antibody, 4930538C18Rik antibody, AI646780 antibody, AW554757 antibody, Smt3ip2 antibody, SuPr-1 antibody, mKIAA1331 antibody, AXAM2 antibody, SMT3IP2 antibody, Axam antibody, SUMO/sentrin specific peptidase 2 antibody, SUMO1/sentrin/SMT3 specific peptidase 2 antibody, Sumo1/sentrin/SMT3 specific peptidase 2 antibody, Senp2 antibody, SENP2 antibody
    Background

    Description: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).

    Gene: SENP2

    Molecular Weight
    68 kDa
    Gene ID
    59343
    UniProt
    Q9HC62
    Pathways
    Chromatin Binding
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