TIMM22 antibody (Internal Region)

Catalog No. ABIN6265572

Product Details anti-TIMM22 Antibody

Target: TIMM22 (Translocase of Inner Mitochondrial Membrane 22 Homolog (TIMM22))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM22 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: TIM22 Antibody detects endogenous levels of total TIM22.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TIM22, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TIMM22

Target: TIMM22 (Translocase of Inner Mitochondrial Membrane 22 Homolog (TIMM22))

Alternative Name: TIMM22 (TIMM22 Products)

Synonyms: 2610511O07Rik antibody, Tim22 antibody, TEX4 antibody, TIM22 antibody, translocase of inner mitochondrial membrane 22 antibody, translocase of inner mitochondrial membrane 22 homolog S homeolog antibody, Timm22 antibody, timm22.S antibody, TIMM22 antibody

Background:

Description: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).

Gene: TIMM22

Molecular Weight: 20 kDa

Gene ID: 29928

UniProt: Q9Y584