TRPC4AP antibody (N-Term)
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- Target See all TRPC4AP Antibodies
- TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRPC4AP antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- TRPC4AP Antibody detects endogenous levels of total TRPC4AP.
- Predicted Reactivity
- Bovine,Horse,Sheep,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TRPC4AP, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))
- Alternative Name
- TRPC4AP (TRPC4AP Products)
- Synonyms
- TRPC4AP antibody, MGC130977 antibody, 4833429F06Rik antibody, D2Ertd113e antibody, Trrp4ap antibody, mFLJ00177 antibody, truss antibody, C20orf188 antibody, TRRP4AP antibody, TRUSS antibody, transient receptor potential cation channel subfamily C member 4 associated protein antibody, transient receptor potential cation channel, subfamily C, member 4 associated protein L homeolog antibody, transient receptor potential cation channel, subfamily C, member 4 associated protein antibody, TRPC4AP antibody, trpc4ap.L antibody, trpc4ap antibody, Trpc4ap antibody
- Background
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Description: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca2+ storage reduction in response to CHRM1.
Gene: TRPC4AP
- Molecular Weight
- 91 kDa
- Gene ID
- 26133
- UniProt
- Q8TEL6
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