TSC22D3 antibody (Internal Region)
-
- Target See all TSC22D3 Antibodies
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
-
Binding Specificity
- Internal Region
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TSC22D3 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Specificity
- TSC-22R Antibody detects endogenous levels of total TSC-22R.
- Predicted Reactivity
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TSC-22R, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TSC22D3 Primary Antibody
-
-
- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
-
- Target
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
- Alternative Name
- TSC22D3 (TSC22D3 Products)
- Synonyms
- dsipi antibody, MGC53285 antibody, zgc:65831 antibody, zgc:77028 antibody, TSC22D3 antibody, GILZ antibody, gilz antibody, tsc-22r antibody, DIP antibody, DSIPI antibody, TSC-22R antibody, hDIP antibody, Dsip1 antibody, Gilz antibody, Tilz3 antibody, Dsipi antibody, DSIP antibody, TSC22 domain family member 3 L homeolog antibody, TSC22 domain family, member 3 antibody, TSC22 domain family member 3 antibody, tsc22d3.L antibody, tsc22d3 antibody, TSC22D3 antibody, Tsc22d3 antibody
- Background
-
Description: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity). Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity).
Gene: TSC22D3
- Molecular Weight
- 15 kDa
- Gene ID
- 1831
- UniProt
- Q99576
-