WNT6 antibody (Internal Region)

Catalog No. ABIN6266045

Product Details anti-WNT6 Antibody

Target: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: WNT6 Antibody detects endogenous levels of total WNT6.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WNT6, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for WNT6

Target: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Alternative Name: WNT6 (WNT6 Products)

Synonyms: WNT6 antibody, si:dkey-31m21.2 antibody, Wnt6 antibody, AA409270 antibody, Wnt-6 antibody, Xwnt-6 antibody, wnt-6 antibody, wnt6-A antibody, xWnt6 antibody, Wnt family member 6 antibody, wingless-type MMTV integration site family, member 6b antibody, wingless-type MMTV integration site family, member 6 antibody, Wnt family member 6 S homeolog antibody, WNT6 antibody, Wnt6 antibody, wnt6b antibody, wnt6.S antibody

Background:

Description: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.

Gene: WNT6

Molecular Weight: 40 kDa

Gene ID: 7475

UniProt: Q9Y6F9

Pathways: WNT Signaling, Tube Formation