GPR18 antibody (Internal Region)

Catalog No. ABIN6281575

Product Details anti-GPR18 Antibody

Target: GPR18 (G Protein-Coupled Receptor 18 (GPR18))

Binding Specificity: AA 160-240, Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: GPR18 is a protein encoded by the GPR18 gene which is approximately 38,1 kDa. GPR18 is localised to the cell membrane. It is involved in peptide ligand-binding receptors and signalling by GPCR. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. It may contribute to the regulation of the immune system and plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure. GPR18 is most abundant in the testis and spleen. STJ93370 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of GPR18 protein.

Specificity: GPR18 Polyclonal Antibody detects endogenous levels of GPR18 protein.

Characteristics: Rabbit polyclonal to GPR18.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GPR18

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000

Comment:

Expressed in midpiece of spermatozoon (at protein level) . Most abundant in testis and spleen . Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for GPR18

Target: GPR18 (G Protein-Coupled Receptor 18 (GPR18))

Alternative Name: GPR18 (GPR18 Products)

Synonyms: GPR18 antibody, G protein-coupled receptor 18 antibody, GPR18 antibody, Gpr18 antibody

Molecular Weight: 34 kDa

Gene ID: 2841

UniProt: Q14330