KCNQ2/3/4/5 (AA 160-240), (pThr217), (pThr223), (pThr246), (pThr251) antibody
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- Target
- KCNQ2/3/4/5
- Binding Specificity
- AA 160-240, pThr217, pThr223, pThr246, pThr251
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit polyclonal to Phospho-KCNQ2/3/4/5 (T217/246/223/251).
- Specificity
- Phospho-KCNQ2/3/4/5 (T217/246/223/251) Polyclonal Antibody detects endogenous levels of KCNQ2/3/4/5 protein only when phosphorylated at T217/246/223/251.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human KCNQ2/3/4/5 around the phosphorylation site of T217/246/223/251.
- Isotype
- IgG
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- Application Notes
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IHC 1:100-1:300
ELISA 1:20000 - Comment
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In adult and fetal brain. Highly expressed in areas containing neuronal cell bodies, low in spinal chord and corpus callosum. Isoform 2 is preferentially expressed in differentiated neurons. Isoform 6 is prominent in fetal brain, undifferentiated neuroblastoma cells and brain tumors.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- KCNQ2/3/4/5
- Molecular Weight
- 96.742 kDa
- Gene ID
- 3785
- UniProt
- O43526
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