CMKLR1 antibody (Internal Region)
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- Target See all CMKLR1 Antibodies
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
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Binding Specificity
- AA 190-270, Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CMKLR1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- ChemR23 is a protein encoded by the CMKLR1 gene which is approximately 42,3 kDa. ChemR23 is localised to the cell membrane. It is involved in the peptide ligand-binding receptors and is a receptor for the chemo-attractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 also induces activation of intracellular signalling molecules. ChemR23 is prominently expressed in developing osseous and cartilaginous tissue. Mutations in the CMKLR1 gene may result in Cataract and Alzheimer's disease. STJ92262 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ChemR23 protein.
- Specificity
- ChemR23 Polyclonal Antibody detects endogenous levels of ChemR23 protein.
- Characteristics
- Rabbit polyclonal to ChemR23.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human ChemR23
- Isotype
- IgG
- Top Product
- Discover our top product CMKLR1 Primary Antibody
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- Application Notes
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WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000 - Comment
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Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow and fetal liver. Among leukocyte populations abundant expression in monocyte-derived macrophage and immature dendritic cells (DCs). High expression in blood monocytes and low levels in polymorphonuclear cells and T-cells. Expressed on endothelial cells. Highly expressed in differentiating adipocytes.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
- Alternative Name
- ChemR23 (CMKLR1 Products)
- Synonyms
- CHEMERINR antibody, ChemR23 antibody, DEZ antibody, RVER1 antibody, Gpcr27 antibody, mcmklr1 antibody, si:ch211-240b21.3 antibody, CMLKR1 antibody, Cmklr-1 antibody, GPCR antibody, chemerin chemokine-like receptor 1 antibody, chemokine-like receptor 1 antibody, CMKLR1 antibody, Cmklr1 antibody, cmklr1 antibody
- Molecular Weight
- 42 kDa
- Gene ID
- 1240
- UniProt
- Q99788
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