ADRB3 antibody (Internal Region)

Catalog No. ABIN6282314

Product Details anti-ADRB3 Antibody

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Binding Specificity: AA 220-300, Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: AR-β3 is a protein encoded by the ADRB3 gene which is approximately 43,5 kDa. AR-β3 is localised to the cell membrane. It is involved in peptide ligand-binding receptors, activation of cAMP-dependent PKA, signalling by GPCR and DAG and IP3 signalling. It mediates catecholamine-induced activation of adenylate cyclase through the action of G proteins and is involved in the regulation of lipolysis and thermogenesis. AR-β3 is expressed mainly in adipose tissue. Mutations in the ADRB3 gene may be involved in diabetes mellitus and obesity. STJ91728 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of AR-β3 protein.

Specificity: AR-β3 Polyclonal Antibody detects endogenous levels of AR-β3 protein.

Characteristics: Rabbit polyclonal to AR-β3.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human AR-beta3

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ELISA 1:20000

Comment:

Expressed mainly in adipose tissues.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for ADRB3

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Alternative Name: AR-beta3 (ADRB3 Products)

Synonyms: BETA3AR antibody, Adrb-3 antibody, ADRB antibody, BAR3 antibody, B3AR antibody, GPCR antibody, im:7154935 antibody, si:ch211-215f19.1 antibody, zgc:194843 antibody, zgc:194852 antibody, adrenoceptor beta 3 antibody, adrenergic receptor, beta 3 antibody, adrenoceptor beta 3a antibody, adrenoceptor beta 3b antibody, ADRB3 antibody, Adrb3 antibody, adrb3a antibody, adrb3b antibody

Molecular Weight: 36 kDa

Gene ID: 155

UniProt: P13945

Pathways: cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation