ADRB3 antibody (Internal Region)
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- Target See all ADRB3 Antibodies
- ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
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Binding Specificity
- AA 220-300, Internal Region
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ADRB3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purpose
- AR-β3 is a protein encoded by the ADRB3 gene which is approximately 43,5 kDa. AR-β3 is localised to the cell membrane. It is involved in peptide ligand-binding receptors, activation of cAMP-dependent PKA, signalling by GPCR and DAG and IP3 signalling. It mediates catecholamine-induced activation of adenylate cyclase through the action of G proteins and is involved in the regulation of lipolysis and thermogenesis. AR-β3 is expressed mainly in adipose tissue. Mutations in the ADRB3 gene may be involved in diabetes mellitus and obesity. STJ91728 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of AR-β3 protein.
- Specificity
- AR-β3 Polyclonal Antibody detects endogenous levels of AR-β3 protein.
- Characteristics
- Rabbit polyclonal to AR-β3.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human AR-beta3
- Isotype
- IgG
- Top Product
- Discover our top product ADRB3 Primary Antibody
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- Application Notes
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WB 1:500-1:2000
ELISA 1:20000 - Comment
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Expressed mainly in adipose tissues.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
- Alternative Name
- AR-beta3 (ADRB3 Products)
- Synonyms
- BETA3AR antibody, Adrb-3 antibody, ADRB antibody, BAR3 antibody, B3AR antibody, GPCR antibody, im:7154935 antibody, si:ch211-215f19.1 antibody, zgc:194843 antibody, zgc:194852 antibody, adrenoceptor beta 3 antibody, adrenergic receptor, beta 3 antibody, adrenoceptor beta 3a antibody, adrenoceptor beta 3b antibody, ADRB3 antibody, Adrb3 antibody, adrb3a antibody, adrb3b antibody
- Molecular Weight
- 36 kDa
- Gene ID
- 155
- UniProt
- P13945
- Pathways
- cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
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