CYP3A4 antibody (Internal Region)

Catalog No. ABIN6282328

Product Details anti-CYP3A4 Antibody

Target: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4/5 (CYP3A4))

Binding Specificity: AA 220-300, Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP3A4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal to CYP3A4/5.

Specificity: CYP3A4/5 Polyclonal Antibody detects endogenous levels of CYP3A4/5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CYP3A4/5

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000

Comment:

Expressed in prostate and liver. According to some authors, it is not expressed in brain . According to others, weak levels of expression are measured in some brain locations . Also expressed in epithelium of the small intestine and large intestine, bile duct, nasal mucosa, kidney, adrenal cortex, epithelium of the gastric mucosa with intestinal metaplasia, gallbladder, intercalated ducts of the pancreas, chief cells of the parathyroid and the corpus luteum of the ovary (at protein level).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for CYP3A4

Target: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4/5 (CYP3A4))

Alternative Name: CYP3A4/5 (CYP3A4 Products)

Synonyms: CYP3A28 antibody, CYP3A4 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody, CYP3A5 antibody

Molecular Weight: 57 kDa

Gene ID: 1576

UniProt: P08684