c-FOS antibody (AA 300-380)
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- Target See all c-FOS (c-Fos) Antibodies
- c-FOS (c-Fos) (c-Fos)
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Binding Specificity
- AA 300-380
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This c-FOS antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- c-Fos is a protein encoded by the FOS gene which is approximately 40,6 kDa. c-Fos is localised to the nucleus, endoplasmic reticulum and cytoplasm. It is involved in activated TLR4 signalling, theIL-2 pathway and toll-like receptor signalling pathways. It is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton. c-Fos is expressed at low levels in quiescent cells. Mutations in the FOS gene may result in cerebral hypoxia and myositis ossificans. STJ92252 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of c-Fos protein.
- Specificity
- C-Fos Polyclonal Antibody detects endogenous levels of c-Fos protein.
- Characteristics
- Rabbit polyclonal to c-Fos.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human c-Fos around the non-phosphorylation site of S374.
- Isotype
- IgG
- Top Product
- Discover our top product c-Fos Primary Antibody
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- Application Notes
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WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- c-FOS (c-Fos) (c-Fos)
- Alternative Name
- c-Fos (c-Fos Products)
- Synonyms
- AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
- Molecular Weight
- 58 kDa
- Gene ID
- 2353
- UniProt
- P01100
- Pathways
- S100 Proteins
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