VGF antibody (Internal Region)

Catalog No. ABIN6284063

Product Details anti-VGF Antibody

Target: VGF (VGF Nerve Growth Factor Inducible (VGF))

Binding Specificity: AA 441-490, Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VGF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: VGF is a protein encoded by the VGF gene which is approximately 67,2 kDa. VGF is secreted and is involved in growth factor activity and neuropeptide hormone activity. VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. It may be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system. VGF is expressed in the central and peripheral nervous systems, it is synthesized exclusively in neuronal and neuroendocrine cells. Mutations in the VGF gene may result in pulmonary large cell Neuroendocrine Carcinoma and Pheochromocytoma. STJ96661 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of VGF protein.

Specificity: VGF Polyclonal Antibody detects endogenous levels of VGF protein.

Characteristics: Rabbit polyclonal to VGF.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human VGF.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000

Comment:

Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for VGF

Target: VGF (VGF Nerve Growth Factor Inducible (VGF))

Alternative Name: VGF (VGF Products)

Synonyms: VGF antibody, Gm1052 antibody, VGF nerve growth factor inducible antibody, VGF antibody, Vgf antibody

Molecular Weight: 67 kDa

Gene ID: 7425

UniProt: O15240

Pathways: Hormone Transport, Carbohydrate Homeostasis