COL1A2 antibody (N-Term)

Catalog No. ABIN6287489

Product Details anti-COL1A2 Antibody

Target: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Binding Specificity: AA 1-80, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL1A2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: COL1A2 is a protein encoded by the COL1A2 gene which is approximately 129,3 kDa. COL1A2 is secreted into the extracellular space. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling and focal adhesion. It is a pro-alpha-2 chain of type I collagen whose triple helix comprises two alpha-1 chains and one alpha-2 chain. COL1A2 is expressed in tendons, ligaments and bones. Mutations in the COL1A2 gene may result in Ehlers-Danlos syndrome and osteogenesis imperfecta. STJ92383 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of COL1A2 protein.

Specificity: COL1A2 Polyclonal Antibody detects endogenous levels of COL1A2 protein.

Characteristics: Rabbit polyclonal to COL1A2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human COL1A2

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000

Comment:

Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for COL1A2

Target: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Alternative Name: COL1A2 (COL1A2 Products)

Synonyms: AA960264 antibody, AI325291 antibody, Col1a-2 antibody, Cola-2 antibody, Cola2 antibody, oim antibody, OI4 antibody, Gas-6 antibody, alpha2(I) antibody, hm:zehn2357 antibody, wu:fa98d05 antibody, wu:fa99g10 antibody, wu:fb04c08 antibody, wu:fb11d06 antibody, zehn2357 antibody, coagulation factor II, thrombin antibody, collagen, type I, alpha 2 antibody, collagen type I alpha 2 chain antibody, collagen type I alpha 2 L homeolog antibody, growth arrest specific 6 antibody, F2 antibody, Col1a2 antibody, col1a2.L antibody, COL1A2 antibody, Gas6 antibody, col1a2 antibody

Molecular Weight: 92 kDa

Gene ID: 1278

UniProt: P08123