USP15 antibody (N-Term)

Catalog No. ABIN6287754

Product Details anti-USP15 Antibody

Target: USP15 (Ubiquitin Specific Peptidase 15 (USP15))

Binding Specificity: AA 50-130, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: USP15 is a protein encoded by the USP15 gene which is approximately 112,4 kDa. USP15 is localised to the cytoplasm and nucleus. It is involved in pathways such as deubiquitination, metabolism of proteins, mitophagy and NF-kappaB signalling. USP15 falls under the ubiquitin specific protease family of deubiquitinating enzymes. It plays a critical role in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. It is a hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways. USP15 is expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovaries. Mutations in the USP15 gene result in speech and communication disorders and isolated microphthalmia. STJ96195 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of USP15 protein.

Specificity: USP15 Polyclonal Antibody detects endogenous levels of USP15 protein.

Characteristics: Rabbit polyclonal to USP15.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human USP15

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ELISA 1:10000

Comment:

Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for USP15

Target: USP15 (Ubiquitin Specific Peptidase 15 (USP15))

Alternative Name: USP15 (USP15 Products)

Synonyms: USP15 antibody, UNP antibody, UNPH-2 antibody, UNPH4 antibody, 4921514G19Rik antibody, AI327321 antibody, E430033I05Rik antibody, Gcap18 antibody, mKIAA0529 antibody, Ubp109 antibody, ubiquitin specific peptidase 15 antibody, universal stress protein UspA antibody, ubiquitin carboxyl-terminal hydrolase 15 antibody, USP15 antibody, RR_RS05795 antibody, LOC100090554 antibody, usp15 antibody, Usp15 antibody

Molecular Weight: 115 kDa

Gene ID: 9958

UniProt: Q9Y4E8