Melatonin Receptor 1A antibody

Catalog No. ABIN6290605

Product Details anti-Melatonin Receptor 1A Antibody

Target: Melatonin Receptor 1A (MTNR1A)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant Protein of human MTNR1A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IHC 1:100 - 1:200

Comment:

Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN), Hippocampus

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: MTNR1A (MTNR1A Products)

Synonyms: MEL-1A-R antibody, MT1 antibody, MTNR1A antibody, MR antibody, MelR antibody, MEL1A antibody, Mel-1A-R antibody, Mel-1A-R-A antibody, Mel1a receptor A antibody, mel1ar antibody, mtnr1ar antibody, zgc:110628 antibody, melatonin receptor 1A antibody, melatonin receptor 1A a antibody, MTNR1A antibody, Mtnr1a antibody, mtnr1aa antibody

Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Molecular Weight: 39.375 kDa

Gene ID: 4543

UniProt: P48039