VRK2 antibody

Catalog No. ABIN6291055

Product Details anti-VRK2 Antibody

Target: VRK2 (Vaccinia Related Kinase 2 (VRK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VRK2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human VRK2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Isoform 1 and isoform 2 are expressed in various tumor cell lines, Expression of isoform 1 inversely correlates with ERBB2 in breast carcinomas (at protein level), Widely expressed, Highly expressed in fetal liver, skeletal muscle, pancreas, heart, peripheral blood leukocytes and testis

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for VRK2

Target: VRK2 (Vaccinia Related Kinase 2 (VRK2))

Alternative Name: VRK2 (VRK2 Products)

Synonyms: 2810003O05Rik antibody, AI447698 antibody, vaccinia related kinase 2 antibody, VRK2 antibody, Vrk2 antibody

Background: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.

Molecular Weight: 58.141 kDa

Gene ID: 7444

UniProt: Q86Y07