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- Target See all ASIP Antibodies
- ASIP (Agouti Signaling Protein (ASIP))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ASIP antibody is un-conjugated
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Application
- Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human ASIP
- Isotype
- IgG
- Top Product
- Discover our top product ASIP Primary Antibody
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anti-Agouti Signaling Protein (ASIP) (AA 23-112) antibody
ASIP Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Agouti Signaling Protein (ASIP) (Internal Region) antibodyASIP Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
anti-Agouti Signaling Protein (ASIP) antibodyASIP Reactivity: Human IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IF 1:50 - 1:200
- Comment
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Expressed in adipose tissue, testis, ovary and heart and at lower levels in liver, kidney and foreskin
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- ASIP (Agouti Signaling Protein (ASIP))
- Alternative Name
- ASIP (ASIP Products)
- Synonyms
- AGSW antibody, AGTI antibody, AGTIL antibody, ASP antibody, SHEP9 antibody, ASIP antibody, AA960621 antibody, AI256638 antibody, D8Ertd580e antibody, PAR-3 antibody, Par3 antibody, Pard3a antibody, agouti signaling protein antibody, par-3 family cell polarity regulator antibody, ASIP antibody, Asip antibody, asip antibody, Pard3 antibody
- Background
- In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
- Molecular Weight
- 14.515 kDa
- Gene ID
- 434
- UniProt
- P42127
- Pathways
- Cell-Cell Junction Organization, Feeding Behaviour
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