INSIG2 antibody

Catalog No. ABIN6291415

Product Details anti-INSIG2 Antibody

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSIG2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human INSIG2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for INSIG2

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Alternative Name: INSIG2 (INSIG2 Products)

Synonyms: MGC82156 antibody, INSIG-2 antibody, 2900053I11Rik antibody, C730043J18Rik antibody, Insig-2 antibody, insulin induced gene 2 antibody, insulin induced gene 2 L homeolog antibody, insig2 antibody, insig2.L antibody, INSIG2 antibody, Insig2 antibody

Background: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Molecular Weight: 24.778 kDa

Gene ID: 51141

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling