AP3B2 antibody

Catalog No. ABIN6291769

Product Details anti-AP3B2 Antibody

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3B2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human AP3B2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expression is specific to nervous system, Expressed in nerve terminal and cell body, and is associated with nerve-terminal vesicles, Expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors and graded in cerebral cortex (deeper layers exhibit stronger expression)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for AP3B2

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Alternative Name: AP3B2 (AP3B2 Products)

Synonyms: AP3B2 antibody, DDBDRAFT_0217414 antibody, DDBDRAFT_0238781 antibody, DDB_0217414 antibody, DDB_0238781 antibody, NAPTB antibody, AI549966 antibody, AU042881 antibody, Naptb antibody, [b]-NAP antibody, beta-NAP antibody, beta3B antibody, adaptor related protein complex 3 beta 2 subunit S homeolog antibody, adaptor related protein complex 3 beta 2 subunit antibody, beta adaptin antibody, adaptor-related protein complex 3, beta 2 subunit antibody, ap3b2.S antibody, AP3B2 antibody, ap3b-2 antibody, ap3b2 antibody, Ap3b2 antibody

Background: Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy.

Molecular Weight: 119.059 kDa

Gene ID: 8120

UniProt: Q13367