ARR3 antibody

Catalog No. ABIN6292647

Product Details anti-ARR3 Antibody

Target: ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARR3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant Protein of human ARR3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Inner and outer segments, and the inner plexiform regions of the retina

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for ARR3

Target: ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))

Alternative Name: ARR3 (ARR3 Products)

Synonyms: ARRX antibody, arr3 antibody, si:bz46j2.6 antibody, zgc:73331 antibody, Arr4 antibody, Car antibody, Carfl antibody, Carr antibody, arr3l antibody, c-arrestin antibody, zgc:92697 antibody, arrestin 3 antibody, arrestin 3, retinal (X-arrestin) L homeolog antibody, arrestin 3, retinal (X-arrestin) antibody, arrestin 3b, retinal (X-arrestin) antibody, arrestin 3, retinal antibody, arrestin 3a, retinal (X-arrestin) antibody, ARR3 antibody, arr3.L antibody, arr3 antibody, arr3b antibody, Arr3 antibody, arr3a antibody

Background: The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function.

Molecular Weight: 42.778 kDa

Gene ID: 407

UniProt: P36575

Pathways: Phototransduction, Thromboxane A2 Receptor Signaling